Maternal-Specific Methylation of the HumanIGF2RGene Is Not Accompanied by Allele-Specific Transcription
نویسندگان
چکیده
منابع مشابه
Maternal-specific methylation of the human IGF2R gene is not accompanied by allele-specific transcription.
The human insulin-like growth factor type 2 receptor gene (IGF2R) is biallelically expressed in a variety of fetal and adult tissues. In contrast, the imprinted mouse Igf2r gene is expressed exclusively from the maternally inherited chromosome. The mouse gene contains two CpG islands that are methylated in a parent-specific manner. Methylation of the CpG island in the promoter region occurs on ...
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ژورنال
عنوان ژورنال: Genomics
سال: 1996
ISSN: 0888-7543
DOI: 10.1006/geno.1996.0027